NT-proBNP levels and diastolic dysfunction in β-Thalassaemia major patients
نویسندگان
چکیده
منابع مشابه
evaluating the correlation between serum nt-probnp level and diastolic dysfunction severity in beta-thalassemia major patients
background: n-terminal pro-brain natriuretic peptide (nt-probnp) is a sensitive biomarker for the detection of asymptomatic left ventricular (lv) dysfunction. since β-thalassemia major patients suffer from early diastolic dysfunction due to iron deposition of chronic blood transfusion, we tried to evaluate the correlation between the serum nt-probnp level and the severity of lv diastolic dysfun...
متن کاملEvaluating the Correlation between Serum NT-proBNP Level and Diastolic Dysfunction Severity in Beta-Thalassemia Major Patients
Background: N-terminal pro-brain natriuretic peptide (NT-proBNP) is a sensitive biomarker for the detection of asymptomatic left ventricular (LV) dysfunction. Since β-thalassemia major patients suffer from early diastolic dysfunction due to iron deposition of chronic blood transfusion, we tried to evaluate the correlation between the serum NT-proBNP level and the severity of LV diastolic dysfun...
متن کاملThe effect of eight weeks of concurrent exercise on NT-proBNP and ferritin serum levels of Beta Thalassemia Major patients
Introduction: Nowadays one of the most important problems of Thalassemia major patients is the additional load of iron and hemosiderosis, the most important consequence of which is deposited iron in myocardial tissue and the incidence of cardiomyopathy caused by hemochromatosis. The aim of this study was to determine the effect of concurrent (resistance-endurance) exercise on NT-pro BNP and...
متن کاملDo plasma levels of brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) increase in diastolic dysfunction as well as in systolic dysfunction?
fter the structure of atrial natriuretic peptide was established,1 a Japanese group isolated the brain (also known as B-type) natriuretic peptide (BNP) from porcine brain extracts in 1988 by monitoring the relaxant activity of the chick rectum.2 Subsequent studies demonstrated that BNP is a cardiac hormone that is mainly expressed in the heart, where its concentration is considerably higher tha...
متن کاملAssociation between serum ferritin level and diastolic cardiac function in patients with major β-thalassemia
Abstract Background Prevention of myocardial siderosis is a key step to reduce rate of mortality in thalassemic patients. Our objective was to study association between echocardiography parameters and serum ferritin level in patients with major thalassemia. Materials and Methods Sixty-six patients with major thalassemia were studied in Amir Kabir hospital, Arak, Iran. Serum ferritin levels ...
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ژورنال
عنوان ژورنال: European Journal of Heart Failure
سال: 2007
ISSN: 1388-9842
DOI: 10.1016/j.ejheart.2006.11.004